Restriction and modification enzymes and their recognition sequences
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چکیده
منابع مشابه
Restriction and modification enzymes and their recognition sequences
Since the last compilation of restriction endonucleases (110), more than 30 Type II restriction endonucleases have been discovered, including some valuable new specificities. These include Acyl (GPuCGPyC), Ddel (CTNAG), Fnu4HI (GCNGC), Rsal (GTAC), SphI (GCAGTC), and XmalH (CGGCCG). In addition, a number of new isoschizomers have been discovered and further information about the recognition seq...
متن کاملRestriction endonucleases and their recognition sequences.
Any survey of Type-I1 restriction endonucleases requires a consideration of the various specificities that are the hallmark of these enzymes. The latest compilation of the restriction-enzyme list contains more than 200 enzymes, which exhibit more than 50 unique specificities (Roberts, 1980). Because these enzymes have demonstrated their greatest value as biochemical tools, classification of the...
متن کاملRestriction enzymes and their isoschizomers.
Since the last compilation of restriction enzymes, (1) 442 new entries have been added including 13 new specificities. A complete list of these new enzymes can be found in Table I. With the growing size of the restriction enzyme database and the recognition that the most widespread use of the information is as a database for computer programs predicting restriction enzyme cleavage patterns, Tab...
متن کاملType I restriction enzymes and their relatives
Type I restriction enzymes (REases) are large pentameric proteins with separate restriction (R), methylation (M) and DNA sequence-recognition (S) subunits. They were the first REases to be discovered and purified, but unlike the enormously useful Type II REases, they have yet to find a place in the enzymatic toolbox of molecular biologists. Type I enzymes have been difficult to characterize, bu...
متن کاملREBASE—enzymes and genes for DNA restriction and modification
REBASE is a comprehensive database of information about restriction enzymes, DNA methyltransferases and related proteins involved in the biological process of restriction-modification. It contains fully referenced information about recognition and cleavage sites, isoschizomers, neoschizomers, commercial availability, methylation sensitivity, crystal and sequence data. Experimentally characteriz...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1980
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/8.1.197-d